This is where it gets fun.
There are guidelines I use for this, but there are no set rules as you are in the hands of fate - mainly because you never know how many pups of each gender you might get and when they will be born, and whether you get single or even a litter at all. Also, the 'odd' ones are the hardest to plan for as you want to avoid singles, so these can catch you out.
The guidelines I follow are simple but half of them can't be guessed at until you actually have the second lot of pups in front of you. However, I think the top 4 - based on my previous answer on the other thread - would be something like:
1) Work to what you already have homes for first - and/or what you are most likely to sell them as.By this I mean if you are homing 3 pairs of males for example, then look to pair those up early - but taking into account your colours. It is easier (for buyers) to have two different colours/patterns in each pair homed together, so to make these pairs you would ideally choose to pair up same litter siblings first; then different litter siblings; and finally non-siblings. If you don't have homes already lined up - then set a deadline to be decisive and create the pairs or quads in advance - especially if they are female pups which you have been keeping in a mixed age and/or mixed litter group.
2) Don't wait beyond 10 weeks for your buyers to choose colours or numbers.This seems counterintuitive at first - as you want to give your buyers the best advantage when buying, but unless these are the only 4 litters you are going to have ever, you will soon get used to the fact that most buyers just (ultimately) want happy healthy gerbils - so do what is best for the gerbils as your priority. If human choice can be fitted into the 'safe' timeline for your pups and their pairing - it is a perfect win:win, but when it is females in groups, mixed ages in mixed litters and the fateful odd gerbils - all getting older - YOU need to be the one making the decisions on their future partners - not your buyers.
3
) Assume you will quadruple your tank numbers with each pairing - but you might need more...After a successful double double-litter, at minimum you will need 4 enclosures by the time the first litters are 4 weeks old (mums in original and dads in new). Depending on numbers/genders/enclosure size/mums attitude you will at some point take out all the pups - and have males in a 5th enclosure and females in the 6th enclosure. That is if all goes well, all ages and genders match up and all are homed early. If you have a lot of pups, with staggered litters with odd numbers of each gender (or all of one gender), where the mums spook out the pups early, they are female heavy and you don't have homes lined up before 12 weeks - it can get a bit hectic for a month or so. When you are breeding, you get used the this sort of 'wave' of expansion with each litter/group of litters splits and splits again, before they all get homed, then you shrink again. The thing with regularly breeding gerbils too though is that by the time you think you have split up enough and have enclosures coming out of your ears - you realise that you already have more pups cooking in the pipeline.
4) Always plan for the leftovers - they take up space.Gerbils you keep who you aren't currently breeding from will take up permanent space ON TOP of your expanding breeding tanks (mentioned above). If you need up to 6 enclosures for your breeding - then you will still have all your permanent non-breeding gerbils in addition to this.
After breeding - many adults can't be paired back together - at least not easily anyway. This means that after your 2 mums and 2 dads have had their two litters each they need to retire (or at least semi retire) with or without pups - so your two original breeding pairs (2 tanks) will almost certainly become 4 permanent tanks in your home - maybe 5 or 6 even if you are breeding mum and/or dad again but still keeping pups yourself. If you want to keep some pups with mum or dad permanently they can certainly stay together in retirement, but if you decide you want to breed from mum, dad or any pups in the future - then assume they won't go back together again afterwards either (so add on another permanent tank for each gerbil split off from an existing group).
If you want to breed gerbils regularly going forward but aren't planning on more than 2 sets of litters per female and you also aren't planning on linebreeding, then you are going to need to source at least 2 more unrelated single gerbils within 6 months to a years time (so 2 more enclosures) - and if you are going to keep any of THEIR pups......
Eek...